Top 20 Global Products, 2010, Total Audited Markets, IMS data

	2010 rank (US$)	2010 Sales (US$ MN)	% Growth 2010 (LC$)	2009 Sales (US$ MN)	% Growth 2009 (LC$)	2008 Sales (US$ MN)	% Growth 2008 (LC$)	2007 Sales (US$ MN)
Global Market	0	791,449$	5.2	752,022$	6.7	727,067$	5.1	671,164$
LIPITOR	1	12,657$	(6.2)	13,288$	(6.2)	13,646$	(0.1)	13,454$
PLAVIX	2	8,817$	(3.4)	9,100$	7.9	8,657$	16.8	7,289$
SERETIDE	3	8,469$	4.4	8,099$	8.9	7,697$	7.3	7,113$
NEXIUM	4	8,362$	1.3	8,236$	7.1	7,828$	8.3	7,146$
SEROQUEL	5	6,816$	13.2	6,012$	13.4	5,376$	15.0	4,619$
CRESTOR	6	6,797$	24.0	5,383$	39.2	3,942$	30.9	2,988$
ENBREL	7	6,167$	5.2	5,863$	9.3	5,521$	8.6	4,998$
REMICADE	8	6,039$	10.3	5,453$	13.1	4,919$	14.9	4,198$
HUMIRA	9	5,960$	19.7	5,032$	31.8	3,941$	43.6	2,692$
ZYPREXA	10	5,737$	6.6	5,357$	9.3	5,026$	(2.2)	5,016$
AVASTIN	11	5,532$	11.1	5,015$	27.2	4,009$	40.2	2,837$
SINGULAIR	12	5,466$	9.2	4,986$	8.9	4,639$	3.9	4,407$
ABILIFY	13	5,430$	16.3	4,673$	31.7	3,574$	30.6	2,714$
MABTHERA	14	5,034$	7.8	4,681$	9.5	4,404$	15.4	3,712$
LANTUS	15	4,686$	16.7	4,019$	21.8	3,406$	27.2	2,651$
ARICEPT	16	4,432$	8.5	4,025$	13.2	3,559$	16.1	2,986$
ACTOS	17	4,317$	3.9	4,124$	9.4	3,757$	8.7	3,407$
LOVENOX	18	4,282$	-5.3	4,577$	8.4	4,362$	9.4	3,902$
HERCEPTIN	19	4,165$	6.7	3,911$	7.9	3,772$	11.6	3,270$
DIOVAN	20	4,157$	3.5	3,930$	5.8	3,678$	10.2	3,178$
Source: IMS Health Midas, December 2010
US$: Sales and Rank are in US$ with quarterly exchange rates
LC$: Growth is in constant $ to normalize for exchange rate fluctuations
Growth rates in US$ are not recommended due to extreme fluctuations in the value of the dollar
Sales cover direct and indirect pharmaceutical channel wholesalers and manufacturers. The figures above include
prescription and certain over the counter data and represent manufacturer prices.